The Suh Lab
Functional Genomics of Human Aging & Longevity
Columbia University Irving Medical Center
Department of Obstetrics and Gynecology
Department of Genetics and Development
Welcome!
The Suh Lab has been taking human genetics and functional genomics approaches to understand the fundamental mechanisms of aging in humans. Aging is the single largest risk-factor for most chronic diseases such as Alzheimer’s disease, cancer, cardiovascular disease, type 2 diabetes, etc. and is emerging as a major component in basic, translational and clinical research. Our long-term research goals are to investigate the genetic component that underlies the interface between intrinsic aging and disease.
Geroscience Hypothesis
Since aging is the greatest risk factor for most chronic ailments, target aging will prevent, delay, and even reverse most human diseases.
Main Research Questions:
Can we identify (epi)genetic signatures of “geroscience” in humans?
What are the fundamental mechanisms of aging underlying geroscience in humans?
Can we apply geroscience to promote healthspan and lifespan in humans?
Genetics of Aging, Aging-related Diseases, and Longevity
Suh Lab in the NEWS
Check out Dr. Suh’s talk
See how we use this functional genomics approach to uncover mechanisms of human longevity-associated genetic variants.
